Lysine (K)-Specific Demethylase 2A (KDM2A) (Middle Region) Peptide
KDM2A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KDM2A products
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KDM2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
- Synonyms
- FBXL11 Peptide, JHDM1A Peptide, 100043628 Peptide, 5530401A10Rik Peptide, AA589516 Peptide, AW536790 Peptide, Cxxc8 Peptide, Fbl11 Peptide, Fbl7 Peptide, Fbxl11 Peptide, Gm4560 Peptide, Jhdm1 Peptide, Jhdm1a Peptide, lalina Peptide, KDM2A Peptide, CXXC8 Peptide, FBL11 Peptide, FBL7 Peptide, LILINA Peptide, fb76b11 Peptide, wu:fb76b11 Peptide, wu:fj11c04 Peptide, zgc:158441 Peptide, zgc:158606 Peptide, lysine demethylase 2A Peptide, lysine (K)-specific demethylase 2A Peptide, lysine (K)-specific demethylase 2Aa Peptide, KDM2A Peptide, Kdm2a Peptide, kdm2aa Peptide
- Background
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
Protein Size: 620 - Molecular Weight
- 68 kDa
- Gene ID
- 22992
- NCBI Accession
- NM_012308, NP_036440
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