Regulator of G-Protein Signaling 17 (RGS17) (C-Term) Peptide
RGS17
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RGS17 products
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Synonyms
- RGS17 Peptide, zgc:92802 Peptide, MGC179306 Peptide, RGS-17 Peptide, RGSZ2 Peptide, hRGS17 Peptide, 6430507P11Rik Peptide, Rgsz2 Peptide, regulator of G protein signaling 17 Peptide, regulator of G-protein signaling 17 Peptide, RGS17 Peptide, Rgs17 Peptide, rgs17 Peptide
- Background
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS-17, RGSZ2, hRGS17
Protein Size: 210 - Molecular Weight
- 23 kDa
- Gene ID
- 26575
- NCBI Accession
- NM_012419, NP_036551
- UniProt
- Q9UGC6
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