Epithelial Splicing Regulatory Protein 2 (ESRP2) (N-Term) Peptide
ESRP2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all ESRP2 products
- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PPPPPGPDPA VDSATDPCPE PQSLVVLFGA TAGALGPDLG SDETDLILLV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Esrp2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
- Synonyms
- RBM35B Peptide, 9530027K23Rik Peptide, Rbm35b Peptide, RGD1310855 Peptide, cb404 Peptide, fa07a06 Peptide, rbm35b Peptide, sb:cb404 Peptide, zgc:77254 Peptide, epithelial splicing regulatory protein 2 Peptide, microRNA 6773 Peptide, ESRP2 Peptide, Esrp2 Peptide, MIR6773 Peptide, esrp2 Peptide
- Background
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Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alias Symbols: 9530027K23Rik, Rbm35b
Protein Size: 717 - Molecular Weight
- 77 kDa
- Gene ID
- 77411
- NCBI Accession
- NM_176838, NP_789808
- UniProt
- Q8K0G8
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