Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptide
U2AF1L4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2185358
$160.46
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100 μg
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Quick Overview for Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptide (ABIN2185358)
Target
Splicing factor U2AF 26 kDa subunit (U2AF1L4)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-U2AF1L4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Splicing factor U2AF 26 kDa subunit (U2AF1L4) peptide
U2AF1L4 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
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Background
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U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Size: 220 -
Molecular Weight
- 24 kDa
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Gene ID
- 199746
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UniProt
- Q8WU68
Target
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