Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptide
U2AF1L4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Splicing factor U2AF 26 kDa subunit (U2AF1L4) products
- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-U2AF1L4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Splicing factor U2AF 26 kDa subunit (U2AF1L4) peptide
U2AF1L4 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
- Synonyms
- U2 small nuclear RNA auxiliary factor 1-like protein 3 Peptide, U2AF1-RS3 Peptide, U2AF1-like 4 Peptide, U2AF1-like protein 3 Peptide, U2AF1L3 Peptide, U2AF1L3V1 Peptide, U2AF1RS3 Peptide, U2af26 Peptide, AA407033 Peptide, AF419339 Peptide, AI451269 Peptide, AW553050 Peptide, TMEM149 Peptide, U2 small nuclear RNA auxiliary factor 1 like 4 Peptide, U2 small nuclear RNA auxiliary factor 1-like 4 Peptide, U2AF1L4 Peptide, U2af1l4 Peptide
- Background
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U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Size: 220 - Molecular Weight
- 24 kDa
- Gene ID
- 199746
- UniProt
- Q8WU68
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