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F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide

FBXW7 Reactivity: Human Host: Rabbit BP

Catalog No. ABIN2763846

Quick Overview for F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide (ABIN2763846)

Target

FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Origin

Human

Source

Rabbit

Application

Blocking Peptide (BP)

F-Box and WD Repeat Domain Containing 7 (FBXW7) peptide
FBXW7 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) peptide
FBXW7 Reactivity: Human Host: Synthetic BP, WB

F-Box and WD Repeat Domain Containing 7 (FBXW7) (Middle Region) peptide
FBXW7 Reactivity: Mouse Host: Synthetic BP, WB, IHC

Restrictions

For Research Use only
Storage

-80 °C
Target

FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Background

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.

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