Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide
ALOX5AP
Reactivity: Human
Host: Rabbit
BP
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- Target See all ALOX5AP products
- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
- Origin
- Human
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Source
- Rabbit
- Application
- Blocking Peptide (BP)
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- Restrictions
- For Research Use only
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- Storage
- -80 °C
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- Target
- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
- Synonyms
- fj65d02 Peptide, zgc:63982 Peptide, wu:fj65d02 Peptide, flap Peptide, al5ap Peptide, Alox5ap Peptide, ALOX5AP Peptide, Flap Peptide, FLAP Peptide, arachidonate 5-lipoxygenase-activating protein Peptide, arachidonate 5-lipoxygenase activating protein Peptide, alox5ap Peptide, ALOX5AP Peptide, Alox5ap Peptide
- Background
- Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
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