(3 references)-
- Target See all RBP3 products
- RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))
- Protein Region
- AA 1-20
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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: "Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs." in: Journal of leukocyte biology, Vol. 97, Issue 6, pp. 1101-9, (2015) (PubMed).
: "Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 8, pp. 4103-11, (2013) (PubMed).
: "Following EAU recovery there is an associated MC5r-dependent APC induction of regulatory immunity in the spleen." in: Investigative ophthalmology & visual science, Vol. 52, Issue 12, pp. 8862-7, (2011) (PubMed).
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: "Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs." in: Journal of leukocyte biology, Vol. 97, Issue 6, pp. 1101-9, (2015) (PubMed).
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- Target
- RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))
- Synonyms
- Irbp Peptide, Rbp-3 Peptide, D10S64 Peptide, D10S65 Peptide, D10S66 Peptide, IRBP Peptide, RBPI Peptide, RP66 Peptide, retinol binding protein 3 Peptide, interphotoreceptor retinoid-binding protein Peptide, retinol binding protein 3, interstitial Peptide, rbp3 Peptide, RBP3 Peptide, glr2547 Peptide, XOO2681 Peptide, AMED_0162 Peptide, ambt_08395 Peptide, Rbp3 Peptide
- Background
- This peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1 -20) induces T-cell-ediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.
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