Sodium/potassium-Transporting ATPase Subunit alpha-1 (AT1A1) (N-Term) Peptide
Quick Overview for Sodium/potassium-Transporting ATPase Subunit alpha-1 (AT1A1) (N-Term) Peptide (ABIN5510812)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- GRDKYEPAAV SEQGDKKGKK GKKDRDMDEL KKEVSMDDHK LSLDELHRKY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AT1A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AT1A1 (Sodium/potassium-Transporting ATPase Subunit alpha-1 (AT1A1))
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Background
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The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ATP1A1,
Protein Size: 1023 -
Gene ID
- 476
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UniProt
- P05023
Target
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