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Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) Peptide

EIF4EBP1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5510913
  • Target See all eIF4EBP1 (EIF4EBP1) products
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    NSPVTKTPPR DLPTIPGVTS PSSDEPPMEA SQSHLRNSPE DKRAGGEESQ
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-4EBP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Synonyms
    4E-BP1 Peptide, 4EBP1 Peptide, BP-1 Peptide, PHAS-I Peptide, 4e-bp1 Peptide, AA959816 Peptide, 153432_at Peptide, 43-BP Peptide, 4E-BP Peptide, 4EBP Peptide, 4e-bp Peptide, 4eBP Peptide, 4ebp Peptide, BcDNA.HL08053 Peptide, BcDNA:HL08053 Peptide, CG8846 Peptide, CT8705 Peptide, Dm 4E-BP Peptide, Dmel\\CG8846 Peptide, Phas1 Peptide, Thor/EIF4EBP Peptide, anon-WO0172774.158 Peptide, d4E-BP Peptide, d4E-BP1 Peptide, d4EBP Peptide, d4e-bp Peptide, d4eBP Peptide, dthor Peptide, eIF4E-BP Peptide, l(2)06270 Peptide, l(2)k07736 Peptide, l(2)k13517 Peptide, pp20 Peptide, thor Peptide, EIF4EBP1 Peptide, fc04h09 Peptide, wu:fc04h09 Peptide, zgc:64137 Peptide, eukaryotic translation initiation factor 4E binding protein 1 Peptide, CG8846 gene product from transcript CG8846-RA Peptide, EIF4EBP1 Peptide, Eif4ebp1 Peptide, Thor Peptide, eif4ebp1 Peptide
    Background
    This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

    Alias Symbols: EIF4EBP1,

    Protein Size: 118
    Gene ID
    1978
    NCBI Accession
    NP_004086
    UniProt
    Q13541
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