Bcl2 Modifying Factor (BMF) (N-Term) Peptide
BMF
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BMF products
- BMF (Bcl2 Modifying Factor (BMF))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MEPSQCVEEL EDDVFQPEDG EPVTQPGSLL SADLFAQSLL DCPLSRLQLF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BMF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BMF (Bcl2 Modifying Factor (BMF))
- Synonyms
- BMF Peptide, AW260063 Peptide, AW411872 Peptide, Bcl2 modifying factor Peptide, Bcl2 modifying factor L homeolog Peptide, BCL2 modifying factor Peptide, BMF Peptide, bmf.L Peptide, Bmf Peptide
- Background
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: BMF,
Protein Size: 129 - Gene ID
- 90427
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