Integrin alpha V (ITGAV) (C-Term) Peptide
ITGAV
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511060
$160.46
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100 μg
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United States
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Quick Overview for Integrin alpha V (ITGAV) (C-Term) Peptide (ABIN5511060)
Target
CD51 (ITGAV)
(Integrin alpha V (ITGAV))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ILAVLAGLLL LAVLVFVMYR MGFFKRVRPP QEEQEREQLQ PHENGEGNSE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- ITGAV Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Background
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The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Alias Symbols: CD51, MSK8, VNRA, VTNR
Protein Size: 1048 -
Gene ID
- 3685
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NCBI Accession
- NM_001144999, NP_001138471
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UniProt
- P06756
Target
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