Dynamin 2 (DNM2) (Middle Region) Peptide
DNM2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511132
$160.46
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100 μg
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Quick Overview for Dynamin 2 (DNM2) (Middle Region) Peptide (ABIN5511132)
Target
DNM2
(Dynamin 2 (DNM2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- IRESLPALRS KLQSQLLSLE KEVEEYKNFR PDDPTRKTKA LLQMVQQFGV
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Characteristics
- This is a synthetic peptide designed for use in combination with DYN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DNM2 (Dynamin 2 (DNM2))
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Background
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Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Alias Symbols: DYN2, CMT2M, DYNII, LCCS5, CMTDI1, CMTDIB, DI-CMTB
Protein Size: 870 -
Gene ID
- 1785
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NCBI Accession
- NM_001005360, NP_001005360
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UniProt
- P50570
Target
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