Dynamin 2 (DNM2) (Middle Region) Peptide
DNM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DNM2 products
- DNM2 (Dynamin 2 (DNM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IRESLPALRS KLQSQLLSLE KEVEEYKNFR PDDPTRKTKA LLQMVQQFGV
- Characteristics
- This is a synthetic peptide designed for use in combination with DYN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DNM2 (Dynamin 2 (DNM2))
- Synonyms
- dynamin-2 Peptide, cmtdi1 Peptide, cmtdib Peptide, dyn2 Peptide, dynII Peptide, CMT2M Peptide, CMTDI1 Peptide, CMTDIB Peptide, DI-CMTB Peptide, DYN2 Peptide, DYNII Peptide, LCCS5 Peptide, Dyn2 Peptide, Udnm Peptide, DYIIAAB Peptide, dnm2 Peptide, zgc:114072 Peptide, dynamin 2 Peptide, dynamin 2 L homeolog Peptide, dynamin 2a Peptide, dynamin 2-like Peptide, DNM2 Peptide, dnm2 Peptide, dnm2.L Peptide, Dnm2 Peptide, dnm2a Peptide, DNM2L Peptide
- Background
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Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Alias Symbols: DYN2, CMT2M, DYNII, LCCS5, CMTDI1, CMTDIB, DI-CMTB
Protein Size: 870 - Gene ID
- 1785
- NCBI Accession
- NM_001005360, NP_001005360
- UniProt
- P50570
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