Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptide
GAD2
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all GAD65 (GAD2) products
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- Synonyms
- GAD65 Peptide, gad65 Peptide, F12P19.12 Peptide, F12P19_12 Peptide, GLUTAMATE DECARBOXYLASE 2 Peptide, glutamate decarboxylase 2 Peptide, zgc:112198 Peptide, 6330404F12Rik Peptide, GAD(65) Peptide, Gad-2 Peptide, glutamate decarboxylase 2 Peptide, glutamate decarboxylase 1 Peptide, glutamic acid decarboxylase 2 Peptide, GAD2 Peptide, PTRG_06148 Peptide, LOC9324534 Peptide, Gad2 Peptide, GAD1 Peptide, gad2 Peptide
- Background
-
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD2,GAD65,
Protein Size: 585 - Gene ID
- 2572
- NCBI Accession
- NP_001127838
- UniProt
- Q05329
-
You are here:
