Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511257
Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN5511257)
Target
HDAC3
(Histone Deacetylase 3 (HDAC3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HDAC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Background
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alias Symbols: HDAC3,
Protein Size: 428 -
Gene ID
- 8841
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NCBI Accession
- NP_003874
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UniProt
- O15379
Target
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