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Histone Deacetylase 3 (HDAC3) (C-Term) Peptide

HDAC3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511258
  • Target See all HDAC3 products
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VQIHDVPADL LTYDRTDEAD AEERGPEENY SRPEAPNEFY DGDHDNDKES
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- HDAC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Synonyms
    CG2128 Peptide, DHDAC3 Peptide, DmHDAC3 Peptide, Dmel\\CG2128 Peptide, Dromel_CG2128_FBtr0078767_hdac3_mORF Peptide, HDAC Peptide, HDAC3 Peptide, Hdac 3 Peptide, dHDAC3 Peptide, dmHDA402 Peptide, hdac3 Peptide, HDm Peptide, hd3 Peptide, RPD3 Peptide, XRpd3 Peptide, rpd3-2 Peptide, HD3 Peptide, RPD3-2 Peptide, AW537363 Peptide, zgc:55927 Peptide, Histone deacetylase 3 Peptide, histone deacetylase 3 Peptide, histone deacetylase 3 S homeolog Peptide, HDAC3 Peptide, hdac3 Peptide, CNL05260 Peptide, Hdac3 Peptide, hdac3.S Peptide
    Background
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

    Alias Symbols: HD3, RPD3, RPD3-2

    Protein Size: 428
    Gene ID
    8841
    NCBI Accession
    NM_003883, NP_003874
    UniProt
    O15379
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