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HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptide

HTRA2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511273
  • Target See all HTRA2 products
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-HTRA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Synonyms
    CG8464 Peptide, DmHtrA2 Peptide, Dmel\\CG8464 Peptide, HtrA2/Omi Peptide, Omi Peptide, dOmi Peptide, domi Peptide, htrA2 Peptide, omi Peptide, HTRA2 Peptide, PRSS25 Peptide, OMI Peptide, PARK13 Peptide, AI481710 Peptide, Prss25 Peptide, mnd2 Peptide, HTRA2-related serine protease Peptide, HtrA serine peptidase 2 Peptide, HtrA2 Peptide, HTRA2 Peptide, htra2 Peptide, Htra2 Peptide
    Background
    This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

    Alias Symbols: OMI, PARK13, PRSS25

    Protein Size: 361
    Gene ID
    27429
    NCBI Accession
    NM_013247, NP_037379
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