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Paired Box 3 (PAX3) (C-Term) Peptide

PAX3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511428
  • Target See all Paired Box 3 (PAX3) products
    Paired Box 3 (PAX3)
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVPFIISSQI
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PAX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Paired Box 3 (PAX3)
    Synonyms
    PAX3 Peptide, cdhs Peptide, hup2 Peptide, pax-3 Peptide, ws1 Peptide, xpax3 Peptide, Pax3 Peptide, pax3 Peptide, pax3b Peptide, xPax3-B Peptide, CDHS Peptide, HUP2 Peptide, WS1 Peptide, WS3 Peptide, Pax-3 Peptide, Sp Peptide, splotch Peptide, zgc:92547 Peptide, paired box 3 Peptide, paired box 3 L homeolog Peptide, paired box 3a Peptide, PAX3 Peptide, pax3 Peptide, pax3.L Peptide, Pax3 Peptide, pax3a Peptide
    Background
    This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

    Alias Symbols: PAX3,HUP2,

    Protein Size: 403
    Gene ID
    5077
    NCBI Accession
    NP_852126
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