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PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1) (Middle Region) Peptide

PMS1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511444
  • Target See all PMS1 products
    PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    PFQNDMHNDE SGKNTDDCLN HQISIGDFGY GHCSSEISNI DKNTKNAFQD
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- PMS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
    Synonyms
    PMSL1 Peptide, si:dz72b14.2 Peptide, si:dz164h20.2 Peptide, PMS1 Peptide, DKFZp468M105 Peptide, pms1 Peptide, HNPCC3 Peptide, hPMS1 Peptide, PMS1 homolog 1, mismatch repair system component Peptide, PMS1 homolog 1, mismatch repair system component S homeolog Peptide, PMS1 Peptide, Pms1 Peptide, pms1 Peptide, pms1.S Peptide
    Background
    This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

    Alias Symbols: MLH2, PMSL1, hPMS1, HNPCC3

    Protein Size: 932
    Gene ID
    5378
    NCBI Accession
    NM_000534, NP_000525
    UniProt
    P54277
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