APOBEC1 Complementation Factor (A1CF) (N-Term) Peptide
A1CF
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all A1CF products
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LGTCPEPEAS MSTAIPGLKK GNNALQSIIL QTLLEKENGQ RKYGGPPPGW
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-A1CF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- A1CF (APOBEC1 Complementation Factor (A1CF))
- Synonyms
- ACF Peptide, ACF64 Peptide, ACF65 Peptide, APOBEC1CF Peptide, ASP Peptide, 1810073H04Rik Peptide, Acf Peptide, A1cft Peptide, Apobec-1 Peptide, acf Peptide, acf64 Peptide, acf65 Peptide, apobec1cf Peptide, asp Peptide, A1CF Peptide, APOBEC1 complementation factor Peptide, apobec1 complementation factor Peptide, APOBEC1 complementation factor L homeolog Peptide, A1CF Peptide, A1cf Peptide, a1cf Peptide, a1cf.L Peptide
- Background
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Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
Protein Size: 659 - Gene ID
- 29974
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