Regulator of Calcineurin 1 (RCAN1) (C-Term) Peptide
RCAN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511914
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Regulator of Calcineurin 1 (RCAN1) (C-Term) Peptide (ABIN5511914)
Target
RCAN1
(Regulator of Calcineurin 1 (RCAN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LHKTEFLGKE MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RCAN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Background
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The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: RCAN1, ADAPT78, CSP1, DSC1, DSCR1,
Protein Size: 252 -
Gene ID
- 1827
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UniProt
- P53805
Target
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