Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (C-Term) Peptide
Quick Overview for Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (C-Term) Peptide (ABIN5512077)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- KIGTPTRPCP LPPGKRSINK LDSPDPFKLN DPFQPFPGND SPKEKDPEIF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- EPS15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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Background
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This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AF1P, AF-1P, MLLT5
Protein Size: 582 -
Gene ID
- 2060
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NCBI Accession
- NM_001159969, NP_001153441
Target
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