Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Peptide
EPS15
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EPS15 products
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EPS15 antibody (Catalog #: ARP54601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Synonyms
- AF-1P Peptide, AF1P Peptide, MLLT5 Peptide, CG16932 Peptide, Dmel\\CG16932 Peptide, EH1 Peptide, EPS-15 Peptide, Eps15 Peptide, anon-WO0118547.85 Peptide, eps-15 Peptide, eps15 Peptide, i31 Peptide, 2410112D09Rik Peptide, RGD1307641 Peptide, epidermal growth factor receptor pathway substrate 15 Peptide, Epidermal growth factor receptor pathway substrate clone 15 Peptide, hypothetical protein Peptide, EPS15 Peptide, Eps-15 Peptide, eps15 Peptide, Eps15 Peptide, PGTG_06574 Peptide
- Background
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EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AF-1P, AF1P, MLLT5
Protein Interaction Partner: AGFG1,AGFG2,CDC40,EPN2,EPN2,NUMB,NUMBL,RNF11,SH3BP4,AGFG1,AGFG2,AP2A1,AP2A2,CRK,DNM1,DNM2,EGFR,ELF3,EPN1,EPN2,EPS15,HGS,ITSN1,LAPTM5,MOBKL3,NAGPA,NEDD4,NUMB,NUMBL,REPS2,RNF11,SNAP91,SPG20,STAM2,STAMBP,STON2,SYNJ1,UBB,UBQLN1,AGFG1,AGFG2,AP2A1,AP2A2,CLINT1,CRK,DNM2,EGFR,EPN1,GRB2,HGS,NAGPA,RAB11FIP2,REPS2,RNF11,SCAMP1,SLC6A3,SNAP91,STAM2,STON2,Synj1,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2H
Protein Size: 896 - Molecular Weight
- 99 kDa
- Gene ID
- 2060
- NCBI Accession
- NM_001981, NP_001972
- UniProt
- P42566
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