Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide
ALAD
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ALAD products
- ALAD (Aminolevulinate Dehydratase (ALAD))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALAD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALAD (Aminolevulinate Dehydratase (ALAD))
- Synonyms
- DDBDRAFT_0190269 Peptide, DDBDRAFT_0231415 Peptide, DDB_0190269 Peptide, DDB_0231415 Peptide, ALAD Peptide, ncf Peptide, ALADH Peptide, PBGS Peptide, ALADR Peptide, aminolevulinatedelta-dehydratase Peptide, zgc:110219 Peptide, Lv Peptide, delta-aminolevulinate dehydratase Peptide, aminolevulinate dehydratase Peptide, delta-aminolevulinic acid dehydratase Peptide, Delta-aminolevulinic acid dehydratase Peptide, aminolevulinate dehydratase L homeolog Peptide, aminolevulinate, delta-, dehydratase Peptide, hemB Peptide, ALAD Peptide, PBGS Peptide, STY0404 Peptide, SAS1597 Peptide, SACI_RS03725 Peptide, PAAG_00299 Peptide, VDBG_00315 Peptide, HPPC_00830 Peptide, MGYG_01952 Peptide, hem2 Peptide, alad.L Peptide, Alad Peptide, alad Peptide
- Background
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: PBGS, ALADH
Protein Size: 330 - Gene ID
- 210
- NCBI Accession
- NM_000031, NP_000022
- UniProt
- P13716
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