Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) (N-Term) Peptide
BATF2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BATF2 products
- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CGGNGLLTQT DPKEQQRQLK KQKNRAAAQR SRQKHTDKAD ALHQQHESLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BATF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
- Synonyms
- RGD1311481 Peptide, BATF2 Peptide, SARI Peptide, 4933430F08Rik Peptide, basic leucine zipper ATF-like transcription factor 2 Peptide, basic leucine zipper transcription factor, ATF-like 2 Peptide, Batf2 Peptide, BATF2 Peptide
- Background
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BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, it participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.
Alias Symbols: BATF2,
Protein Size: 274 - Gene ID
- 116071
- UniProt
- Q8N1L9
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