Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide
CIDEA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CIDEA products
- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PARPFRVSNH DRSSRRGVMA SSLQELISKT LDALVIATGL VTLVLEEDGT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CIDEA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
- Synonyms
- CIDE-A Peptide, AW212747 Peptide, CIDEA Peptide, cide-a Peptide, MGC89985 Peptide, cell death-inducing DFFA-like effector a Peptide, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A Peptide, cell death-inducing DFFA-like effector a L homeolog Peptide, CIDEA Peptide, Cidea Peptide, cidea Peptide, cidea.L Peptide
- Background
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This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Alias Symbols: CIDE-A
Protein Size: 219 - Gene ID
- 1149
- NCBI Accession
- NM_001279, NP_001270
- UniProt
- O60543
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