Death-Domain Associated Protein (DAXX) (N-Term) Peptide
DAXX
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512286
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Death-Domain Associated Protein (DAXX) (N-Term) Peptide (ABIN5512286)
Target
DAXX
(Death-Domain Associated Protein (DAXX))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- KLNLAPAATT SNEPSGNNPP THLSLDPTNA ENTASQSPRT RGSRRQIQRL
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-DAXX Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- DAXX (Death-Domain Associated Protein (DAXX))
-
Background
-
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Alias Symbols: Name=DAXX,
Protein Size: 740 -
Gene ID
- 1616
-
NCBI Accession
- NP_001341
-
UniProt
- Q9UER7
Target
-
You are here:
