Dihydrodiol Dehydrogenase (DDH) (Middle Region) Peptide
DDH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512291
Quick Overview for Dihydrodiol Dehydrogenase (DDH) (Middle Region) Peptide (ABIN5512291)
Target
AKR1C1 (DDH)
(Dihydrodiol Dehydrogenase (DDH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KIADGSVKRE DIFYTSKLWC NSHRPELVRP ALERSLKNLQ LDYVDLYLIH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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Background
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD
Protein Size: 323 -
Gene ID
- 1645
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NCBI Accession
- NP_001344
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UniProt
- Q04828
Target
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