Dihydrodiol Dehydrogenase (DDH) (N-Term) Peptide
DDH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AKR1C1 (DDH) products
- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DSAHLYNNEE QVGLAIRSKI ADGSVKREDI FYTSKLWCNS HRPELVRPAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
- Synonyms
- 2-ALPHA-HSD Peptide, 20-ALPHA-HSD Peptide, C9 Peptide, DD1 Peptide, DD1/DD2 Peptide, DDH Peptide, DDH1 Peptide, H-37 Peptide, HAKRC Peptide, HBAB Peptide, MBAB Peptide, aldo-keto reductase family 1 member C1 Peptide, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) Peptide, AKR1C1 Peptide
- Background
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
Protein Size: 323 - Molecular Weight
- 36 kDa
- Gene ID
- 1645
- NCBI Accession
- NM_001353, NP_001344
- UniProt
- Q04828
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