Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptide
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- Target See all HSD17B10 products
- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VAGEMGQNEP DQGGQRGVII NTASVAAFEG QVGQAAYSAS KGGIVGMTLP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- HSD17B10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
- Synonyms
- hadh2 Peptide, im:6899159 Peptide, wu:fj61f03 Peptide, zgc:101605 Peptide, abad Peptide, camr Peptide, erab Peptide, hcd2 Peptide, hsd10 Peptide, mhbd Peptide, mrpp2 Peptide, mrx17 Peptide, mrx31 Peptide, mrxs10 Peptide, schad Peptide, sdr5c1 Peptide, HADH2 Peptide, HSD17B10 Peptide, 17b-HSD10 Peptide, ABAD Peptide, CAMR Peptide, DUPXp11.22 Peptide, ERAB Peptide, HCD2 Peptide, MHBD Peptide, MRPP2 Peptide, MRX17 Peptide, MRX31 Peptide, MRXS10 Peptide, SCHAD Peptide, SDR5C1 Peptide, 17bHSD10 Peptide, Ads9 Peptide, Hadh2 Peptide, hydroxysteroid (17-beta) dehydrogenase 10 Peptide, hydroxysteroid 17-beta dehydrogenase 10 Peptide, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog Peptide, HSD17B10 Peptide, hsd17b10 Peptide, hsd17b10.L Peptide, Hsd17b10 Peptide
- Background
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This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22
Protein Size: 261 - Gene ID
- 3028
- NCBI Accession
- NM_001037811, NP_001032900
- UniProt
- Q99714
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