Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF) (N-Term) Peptide
LITAF
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512399
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF) (N-Term) Peptide (ABIN5512399)
Target
LITAF
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LITAF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
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Background
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Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: LITAF,PIG7,SIMPLE,
Protein Size: 228 -
Gene ID
- 9516
Target
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