Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (N-Term) Peptide
MAP2K7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAP2K7 products
- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LNLDISPQRP RPTLQLPLAN DGGSRSPSSE SSPQHPTPPA RPRHMLGLPS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAP2K7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
- Synonyms
- MAP2K7 Peptide, 2 Peptide, JNKK Peptide, Jnkk2 Peptide, Mapkk7 Peptide, Mek7 Peptide, Mkk7 Peptide, MAPKK7 Peptide, MKK7 Peptide, PRKMK7 Peptide, SAPKK-4 Peptide, SAPKK4 Peptide, 5930412N11Rik Peptide, JNKK 2 Peptide, MAPKK 7 Peptide, MEK 7 Peptide, Prkmk7 Peptide, sek2 Peptide, si:ch211-254d18.2 Peptide, map2k7-A Peptide, mitogen-activated protein kinase kinase 7 Peptide, mitogen activated protein kinase kinase 7 Peptide, mitogen-activated protein kinase kinase 7 L homeolog Peptide, MAP2K7 Peptide, Map2k7 Peptide, map2k7 Peptide, map2k7.L Peptide
- Background
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The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Alias Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4
Protein Size: 462 - Gene ID
- 5609
- NCBI Accession
- NM_001297555, NP_660186
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