Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) (Middle Region) Peptide
Quick Overview for Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) (Middle Region) Peptide (ABIN5512441)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- LPESLASLHP SVSPGSPPPP LPNHKYNTTS TSYSPLASLP LKADTKGFCN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLAGL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
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Background
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This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.
Alias Symbols: ZAC, LOT1, ZAC1
Protein Size: 411 -
Gene ID
- 5325
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NCBI Accession
- NM_001080951, NP_001074420
Target
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