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Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) (Middle Region) Peptide

PLAGL1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512441
  • Target See all PLAGL1 products
    PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LPESLASLHP SVSPGSPPPP LPNHKYNTTS TSYSPLASLP LKADTKGFCN
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PLAGL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
    Synonyms
    PLAGL1 Peptide, LOT1 Peptide, ZAC Peptide, ZAC1 Peptide, Lot1 Peptide, Zac1 Peptide, PLAG1 like zinc finger 1 Peptide, uncharacterized LOC100350914 Peptide, pleiomorphic adenoma gene-like 1 Peptide, PLAGL1 Peptide, LOC100350914 Peptide, Plagl1 Peptide
    Background
    This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.

    Alias Symbols: ZAC, LOT1, ZAC1

    Protein Size: 411
    Gene ID
    5325
    NCBI Accession
    NM_001080951, NP_001074420
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