Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72) Peptide
VPS72
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all VPS72 products
- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-VPS72 antibody (Catalog #: ARP74345_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
- Synonyms
- CG4621 Peptide, Dmel\\CG4621 Peptide, dYL-1 Peptide, vps72 Peptide, MGC82727 Peptide, Vps72 Peptide, YL-1 Peptide, ACYPI009531 Peptide, Tcfl1 Peptide, CFL1 Peptide, Swc2 Peptide, TCFL1 Peptide, YL1 Peptide, si:dkeyp-24a7.1 Peptide, CG4621 gene product from transcript CG4621-RB Peptide, vacuolar protein sorting 72 homolog L homeolog Peptide, potential vacuolar protein sorting protein Peptide, vacuolar protein sorting 72 homolog Peptide, vacuolar protein sorting-associated protein 72 homolog Peptide, vacuolar protein sorting 72 Peptide, vacuolar protein sorting 72 homolog S homeolog Peptide, vacuolar protein sorting 72 homolog (S. cerevisiae) Peptide, YL-1 Peptide, vps72.L Peptide, VPS72 Peptide, Vps72 Peptide, vps72.S Peptide, vps72 Peptide
- Background
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The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Alias Symbols: TCFL1, YL1
Protein Size: 364 - Molecular Weight
- 40 kDa
- Gene ID
- 6944
- NCBI Accession
- NP_005988
- UniProt
- Q15906
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