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Phytanoyl-CoA 2-Hydroxylase (PHYH) (Middle Region) Peptide

PHYH Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5512523
  • Target See all PHYH products
    PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VVLPGTHKGS LKPHDYPKWE GGVNKMFHGI QDYEENKARV HLVMEKGDTV
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- PHYH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))
    Synonyms
    zgc:110203 Peptide, LN1 Peptide, LNAP1 Peptide, PAHX Peptide, PHYH1 Peptide, RD Peptide, AI256161 Peptide, AI265699 Peptide, Lnap1 Peptide, phytanoyl-CoA 2-hydroxylase Peptide, phytanoyl-CoA hydroxylase-like Peptide, phytanoyl-CoA hydroxylase Peptide, PHYH Peptide, LOC478001 Peptide, phyh Peptide, Phyh Peptide
    Background
    This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Alias Symbols: RD, LN1, PAHX, LNAP1, PHYH1

    Protein Size: 338
    Gene ID
    5264
    NCBI Accession
    NM_001037537, NP_006205
    UniProt
    O14832
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