Calsyntenin 1 (CLSTN1) (C-Term) Peptide
Quick Overview for Calsyntenin 1 (CLSTN1) (C-Term) Peptide (ABIN5512532)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- RTMRDQDTGK ENEMDWDDSA LTITVNPMET YEDQHSSEEE EEEEEEEESE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- WDR48 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Calsyntenin 1 (CLSTN1)
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Background
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This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: CST-1, CSTN1, CDHR12, PIK3CD, ALC-ALPHA, XB31alpha, alcalpha1, alcalpha2
Protein Size: 981 -
Gene ID
- 22883
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NCBI Accession
- NM_001009566, NP_001009566
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UniProt
- O94985
Target
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