Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2) (Middle Region) Peptide
DPM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DPM2 products
- DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DSQHVIHKYF LPRAYAVAIP LAAGLLLLLF VGLFISYVML KTKRVTKKAQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- DPM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DPM2 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 2, Regulatory Subunit (DPM2))
- Synonyms
- dpm2b Peptide, dpm2a Peptide, AW557993 Peptide, R75484 Peptide, CDG1U Peptide, wu:fa99c01 Peptide, zgc:112514 Peptide, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit S homeolog Peptide, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit L homeolog Peptide, dolichol-phosphate (beta-D) mannosyltransferase 2 Peptide, dolichyl-phosphate mannosyltransferase subunit 2, regulatory Peptide, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit Peptide, dpm2.S Peptide, dpm2.L Peptide, Dpm2 Peptide, DPM2 Peptide, dpm2 Peptide
- Background
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Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
Alias Symbols: CDG1U
Protein Size: 84 - Gene ID
- 8818
- NCBI Accession
- NM_003863, NP_003854
- UniProt
- O94777
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