Chromobox Homolog 7 (CBX7) Peptide
CBX7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CBX7 products
- CBX7 (Chromobox Homolog 7 (CBX7))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CBX7 antibody (Catalog #: ARP74429_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CBX7 (Chromobox Homolog 7 (CBX7))
- Synonyms
- 1600014J01Rik Peptide, AI851678 Peptide, D15Ertd417e Peptide, zgc:110152 Peptide, chromobox 7 Peptide, chromobox homolog 7a Peptide, CBX7 Peptide, Cbx7 Peptide, cbx7a Peptide
- Background
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CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Protein Size: 251 - Molecular Weight
- 27 kDa
- Gene ID
- 23492
- NCBI Accession
- NP_783640
- UniProt
- O95931
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