5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (MTHFS) (Middle Region) Peptide
MTHFS
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MTHFS products
- MTHFS (5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (MTHFS))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GLGFDKHGNR LGRGKGYYDA YLKRCLQHQE VKPYTLALAF KEQICLQVPV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MTHFS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MTHFS (5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase) (MTHFS))
- Synonyms
- MTHFS Peptide, 1110034I12Rik Peptide, 2310020H23Rik Peptide, AI119695 Peptide, HsT19268 Peptide, 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) Peptide, methenyltetrahydrofolate synthetase Peptide, 5-formyltetrahydrofolate cyclo-ligase (predicted) Peptide, 5-formyltetrahydrofolate cyclo-ligase Peptide, 5, 10-methenyltetrahydrofolate synthetase Peptide, MTHFS Peptide, SPBC1703.08c Peptide, ZMO0215 Peptide, LBA1507 Peptide, Rxyl_1321 Peptide, MEMAR_RS07640 Peptide, Mjls_4669 Peptide, STROP_RS03755 Peptide, Mext_0779 Peptide, AMF_RS07350 Peptide, CKC_02040 Peptide, Mthfs Peptide
- Background
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The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HsT19268
Protein Size: 203 - Gene ID
- 10588
- NCBI Accession
- NM_001199758, NP_001186687
- UniProt
- P49914
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