Carbonic Anhydrase VB, Mitochondrial (CA5B) (Middle Region) Peptide
CA5B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512783
$160.46
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100 μg
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United States
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Quick Overview for Carbonic Anhydrase VB, Mitochondrial (CA5B) (Middle Region) Peptide (ABIN5512783)
Target
CA5B
(Carbonic Anhydrase VB, Mitochondrial (CA5B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TLLFTSEGEK EKRMVDNFRP LQPLMNRTVR SSFRHDYVLN VQAKPKPATS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CA5B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))
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Background
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
Alias Symbols: CA-VB
Protein Size: 317 -
Gene ID
- 11238
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NCBI Accession
- NM_007220, NP_009151
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UniProt
- Q9Y2D0
Target
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