Carbonic Anhydrase VB, Mitochondrial (CA5B) (N-Term) Peptide
Quick Overview for Carbonic Anhydrase VB, Mitochondrial (CA5B) (N-Term) Peptide (ABIN974340)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- WRDSVYDPGL KPLTISYDPA TCLHVWNNGY SFLVEFEDST DKSVIKGGPL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CA5B Antibody(ARP52303_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))
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Background
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
Alias Symbols: CA-VB, MGC39962
Protein Size: 317 -
Molecular Weight
- 33 kDa
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Gene ID
- 11238
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NCBI Accession
- NM_007220, NP_009151
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UniProt
- Q9Y2D0
Target
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