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Carbonic Anhydrase VB, Mitochondrial (CA5B) (N-Term) Peptide

CA5B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974340
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for Carbonic Anhydrase VB, Mitochondrial (CA5B) (N-Term) Peptide (ABIN974340)

Target

CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))

Origin

Human

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    WRDSVYDPGL KPLTISYDPA TCLHVWNNGY SFLVEFEDST DKSVIKGGPL

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-CA5B Antibody(ARP52303_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))

    Background

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.

    Alias Symbols: CA-VB, MGC39962

    Protein Size: 317

    Molecular Weight

    33 kDa

    Gene ID

    11238

    NCBI Accession

    NM_007220, NP_009151

    UniProt

    Q9Y2D0
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