Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptide
BTK
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BTK products
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTVHKLSYYE YDFERGRRGS KKGSIDVEKI TCVETVVPEK NPPPERQIPR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BTK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Synonyms
- BTK Peptide, atk Peptide, bpk Peptide, xla Peptide, imd1 Peptide, agmx1 Peptide, psctk1 Peptide, AGMX1 Peptide, AT Peptide, ATK Peptide, BPK Peptide, IMD1 Peptide, PSCTK1 Peptide, XLA Peptide, AI528679 Peptide, xid Peptide, Bruton tyrosine kinase Peptide, Bruton agammaglobulinemia tyrosine kinase Peptide, BTK Peptide, btk Peptide, Btk Peptide
- Background
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1
Protein Size: 483 - Gene ID
- 695
- NCBI Accession
- NM_000061, NP_000052
- UniProt
- Q5JY90
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