Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (Middle Region) Peptide
CASP9
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Caspase 9 (CASP9) products
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QKDHGFEVAS TSPEDESPGS NPEPDATPFQ EGLRTFDQLD AISSLPTPSD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CASP9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Synonyms
- CASP9 Peptide, AI115399 Peptide, APAF-3 Peptide, AW493809 Peptide, CASP-9 Peptide, Caspase-9 Peptide, ICE-LAP6 Peptide, Mch6 Peptide, Apaf3 Peptide, Casp-9-CTD Peptide, Casp9_v1 Peptide, Ice-Lap6 Peptide, APAF3 Peptide, MCH6 Peptide, PPP1R56 Peptide, caspase 9 Peptide, CASP9 Peptide, Casp9 Peptide
- Background
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Alias Symbols: CASP9, MCH6,
Protein Size: 266 - Gene ID
- 842
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