Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide
-
- Target See all LCK products
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LCK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- Synonyms
-
zgc:136695 Peptide, LCK Peptide, Hck-3 Peptide, Lsk Peptide, Lskt Peptide, p56
Peptide, p56Lck Peptide, LSK Peptide, YT16 Peptide, p56lck Peptide, pp58lck Peptide, P56LCK Peptide, tkl Peptide, Lck1 Peptide, Lcktkr Peptide, LCK proto-oncogene, Src family tyrosine kinase Peptide, lymphocyte protein tyrosine kinase Peptide, lck Peptide, LCK Peptide, Lck Peptide - Background
-
LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
Protein Size: 363 - Gene ID
- 3932
-