UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide
UGDH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513172
$160.46
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100 μg
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Quick Overview for UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide (ABIN5513172)
Target
UGDH
(UDP-Glucose 6-Dehydrogenase (UGDH))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LDGLHNELQT IGFQIETIGK KVSSKRIPYA PSGEIPKFSL QDPPNKKPKV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- UGDH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Background
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The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Alias Symbols: GDH, UGD, UDPGDH, UDP-GlcDH
Protein Size: 494 -
Gene ID
- 7358
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NCBI Accession
- NM_001184700, NP_001171629
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UniProt
- O60701
Target
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