UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide
Quick Overview for UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide (ABIN985899)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UGDH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Background
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The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD
Protein Interaction Partner: AK5,AK5
Protein Size: 494 -
Molecular Weight
- 54 kDa
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Gene ID
- 7358
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NCBI Accession
- NM_003359, NP_003350
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UniProt
- O60701
Target
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