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UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide

UGDH Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985899
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
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Quick Overview for UDP-Glucose 6-Dehydrogenase (UGDH) (C-Term) Peptide (ABIN985899)

Target

UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-UGDH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

    Background

    The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.

    Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD

    Protein Interaction Partner: AK5,AK5

    Protein Size: 494

    Molecular Weight

    54 kDa

    Gene ID

    7358

    NCBI Accession

    NM_003359, NP_003350

    UniProt

    O60701
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