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Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide

IL3RA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5513352

Quick Overview for Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide (ABIN5513352)

Target

IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    CRRYLVMQRL FPRIPHMKDP IGDSFQNDKL VVWEAGKAGL EECLVTEVQV

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-IL3RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

    Background

    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

    Alias Symbols: IL3RA,IL3R,

    Protein Size: 378

    Gene ID

    3563

    NCBI Accession

    XP_005274837

    UniProt

    P26951
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