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Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptide

IL3RA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN978509
  • Target See all IL3RA products
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    IQKRMQPVIT EQVRDRTSFQ LLNPGTYTVQ IRARERVYEF LSAWSTPQRF
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-IL3RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Synonyms
    CD123 Peptide, IL3R Peptide, IL3RAY Peptide, IL3RX Peptide, IL3RY Peptide, hIL-3Ra Peptide, CDw123 Peptide, SUT-1 Peptide, Cyrl Peptide, interleukin 3 receptor subunit alpha Peptide, interleukin 3 receptor, alpha chain Peptide, IL3RA Peptide, Il3ra Peptide
    Background
    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.

    Alias Symbols: CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra

    Protein Interaction Partner: CISH,CSF2,CSF2RB,IL3,JAK1,JAK2,CISH,IL3

    Protein Size: 378
    Molecular Weight
    41 kDa
    Gene ID
    3563
    NCBI Accession
    NM_002183, NP_002174
    UniProt
    P26951
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