POU Class 5 Homeobox 1 (POU5F1) (N-Term) Peptide
POU5F1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OCT4 (POU5F1) products
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MHFYRLFLGA TRRFLNPEWK GEIDNWCVYV LTSLLPFKIQ SQDIKALQKE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- POU5F1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- Synonyms
- OCT3 Peptide, OCT4 Peptide, OTF-3 Peptide, OTF3 Peptide, OTF4 Peptide, Oct-3 Peptide, Oct-4 Peptide, POU5F1 Peptide, gp9 Peptide, gp-9 Peptide, oct4 Peptide, pou2 Peptide, POU-2 Peptide, cb197 Peptide, spg/pou2 Peptide, chunp6868 Peptide, wu:fd18d06 Peptide, NF-A3 Peptide, Oct-3/4 Peptide, Oct3 Peptide, Oct3/4 Peptide, Oct4 Peptide, Otf-3 Peptide, Otf-4 Peptide, Otf3 Peptide, Otf3-rs7 Peptide, Otf3g Peptide, Otf4 Peptide, POU class 5 homeobox 1 Peptide, POU domain, class 5, transcription factor 3 Peptide, POU domain, class 5, transcription factor 1 Peptide, POU5F1 Peptide, pou5f3 Peptide, Pou5f1 Peptide
- Background
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This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Alias Symbols: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
Protein Size: 265 - Gene ID
- 5460
- NCBI Accession
- NM_001285987, NP_001272916
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