Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (Middle Region) Peptide
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- Target See all Pellino 1 (PELI1) products
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SMKRKDVVDE KQPWVYLNCG HVHGYHNWGN KEERDGKDRE CPMCRSVGPY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PELI1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
- Synonyms
- 2810468L03Rik Peptide, A930031K15Rik Peptide, AA409794 Peptide, AI586297 Peptide, D11Ertd676e Peptide, peli1 Peptide, peli1.L Peptide, pellino1 Peptide, xpellino1 Peptide, wu:fd12d01 Peptide, zgc:153297 Peptide, pellino E3 ubiquitin protein ligase 1 Peptide, pellino 1 Peptide, pellino E3 ubiquitin protein ligase 1 S homeolog Peptide, pellino E3 ubiquitin protein ligase 1b Peptide, PELI1 Peptide, Peli1 Peptide, peli1.S Peptide, peli1b Peptide
- Background
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E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.
Protein Size: 418 - Gene ID
- 57162
- NCBI Accession
- NM_020651, NP_065702
- UniProt
- Q96FA3
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