RAR-Related Orphan Receptor C (RORC) (Middle Region) Peptide
RORC
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513532
Quick Overview for RAR-Related Orphan Receptor C (RORC) (Middle Region) Peptide (ABIN5513532)
Target
RORC
(RAR-Related Orphan Receptor C (RORC))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PGLGELGQGP DSYGSPSFRS TPEAPYASLT EIEHLVQSVC KSYRETCQLR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RORC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Background
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The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RORC, NR1F3, RORG, RZRG,
Protein Size: 518 -
Gene ID
- 6097
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NCBI Accession
- NP_005051
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UniProt
- P51449
Target
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